Leonard Levin

Titre 

• Professeur agrégé
• Titulaire de la Chaire de recherche du Canada en ophtalmologie et sciences visuelles

FORMATION

• Ph.D., Harvard University, Department of Neurobiology. Thesis: Immune Functions of Astrocytes; Thesis Advisor: Howard L. Weiner, M.D. (1988).
• M.D., Harvard Medical School and Harvard-MIT Program in Health Sciences and Technology. (1988).
• Fellow in Neuro-Ophthalmology (Simmons Lessell and Joseph Rizzo, preceptors), Massachusetts Eye and Ear Infirmary, Boston, MA. (1992)

DISTINCTIONS ET RÉALISATIONS

• Grass Foundation fellowship. (1983)   
• NATO fellowship for Advanced Study Institute. (1984)       
• Heed Foundation fellowship. (1992-93)  
• National Eye Institute Travel Fellowship. (1993)       
• Rudin Prize paper co-author. (1996)       
• North American Neuro-Ophthalmology Society Young Investigator Award. (1997)       
• Research to Prevent Blindness Dolly Green Special Scholar Award. (1997)       
• Retina Research Foundation Sam and Bertha Brochstein Award. (1997)       
• Listed in The Best Doctors in America® 1999 
• Japan Society for the Promotion of Science Fellowship. (1999)        
• Listed in The Best Doctors in America® 2001-2
• Retina Research Foundation Marjorie W. Margolin Prize. (2003) 
• Listed in The Best Doctors in America® 2003-4
• Retina Research Foundation Sam and Bertha Brochstein Award. (2004)       
• Listed in The Best Doctors in America® 2005-6
• Listed in The Best Doctors in America® 2007-8

PERSONNEL DE RECHERCHE

• Katrina Mears (maîtrise)
• Rachel Beaubien (maîtrise) 

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INTÉRêTS DE RECHERCHE

• Mécanismes de signalisation intracellulaire de la mort des cellules rétiniennes après dommage axonal - Glaucome et autres neuropathies optiques
• Neuroprotection des neurones rétiniennes dans la neuropathie optique et la DMLA
• Différentiation des cellules souches des cellules rétiniennes ganglionnaires

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PUBLICATIONS CHOISIES  

• Schlieve CR, Lieven CJ, Levin LA. Biochemical activity of reactive oxygen species scavengers do not predict retinal ganglion cell survival. Invest Ophthalmol Vis Sci, 47:3878-86, 2006.
• Niederkohr RD, Levin LA. A Bayesian analysis of the true sensitivity of a temporal artery biopsy. Invest Ophthalmol Vis Sci, 48:675-680, 2007.
• Vrabec JP, Levin LA. Type II protein C deficiency in a sixteen-year-old girl with central retinal vein occlusion. Am J Ophthalmol, 143:341-342, 2007.
•  Nguyen SM, Lieven CJ, Levin LA. Simultaneous labeling of projecting neurons and apoptotic state, J Neurosci Methods 161:281-284, 2007.
• Levin LA. Axonal loss and neuroprotection in optic neuropathies. Can J Ophthalmol, 42:403-408, 2007.
• Schwechter BR, Millet LE, Levin LA. Histone deacetylase inhibition-mediated differentiation of RGC-5 cells and interaction with survival. Invest Ophthalmol Vis Sci 48:2845-2857, 2007.
• Lieven CJ, Millet LE, Levin LA. Induction of axon and dendrite formation during early RGC-5 cell differentiation. Exp Eye Res, dx.doi.org/10.1016/j.exer.2007.08.001. 
• Levin LA. The Ischemic Optic Nerve Compression Decompression Trial: A decade later. Arch Ophthalmol, in press. 
• Levin LA, Mechanisms of retinal ganglion specific-cell death in Leber’s hereditary optic neuropathy. Trans Am Ophthalmol Soc, in press.
• Hoegger MJ, Levin LA. Differential production of superoxide by neuronal mitochondria. BMC Neurosci. 2008 Jan 8;9:4.  

Liste complète des publications du Dr Levin (PubMed)

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INFORMATIONS COMPLEMENTAIRES

Collaborations

•  Adriana DiPolo, Université de Montréal

Subventions

• Chaire de recherche du Canada en ophtalmologie et sciences visuelles
• IRSC
• National Eye Institute (E.U.)
• FCI

 

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