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Louis-Philippe Laurin

Laurin, Louis-Philippe

Assistant clinical professor

Affiliation

Université de Montréal

Research Axes

Nephrology

Contact information

Phone: 514-252-3400, poste2919

lplaurin.hmr@ssss.gouv.qc.ca

Team

  • Mukelda Mikye Castor
  • Karine Chaussé

Dr. Louis-Philippe Laurin directs the Glomerular Diseases Research Unit. He is also an assistant clinical professor in the Faculty of Medicine at Université de Montréal.

In addition to his clinical activities as a nephrologist with the CIUSSS de l’Est-de-l’Île-de-Montréal and the Montreal Heart Institute, Dr. Laurin directs a clinic that specializes in glomerular diseases at Hôpital Maisonneuve-Rosemont.

Research Unit

Glomerular Diseases

Glomerular diseases are a group of diseases that damage the glomerulus, or the kidney's filtration unit. These diseases affect many people with end-stage kidney disease who require dialysis. Glomerular diseases represent a significant and extended individual and societal burden, as they mainly affect young people and the progression from onset to end-stage kidney disease takes many years. Although common as a whole, they are individually rare. This heterogeneity and the time from onset to end-stage kidney disease have hindered the development of new treatments through clinical studies. The creation of a large cohort of patients with glomerular diseases will allow us to effectively support research in this area of medical study.

The research program of Dr. Laurin's team consists of studying the epidemiology of glomerulopathies. In 2015, his research unit launched a local registry of patients with glomerular diseases. This patient cohort serves as a platform for local and international projects.

  • Laurin LP, Nachman PH, Foster BJ. Calcineurin Inhibitors in the Treatment of Primary Focal Segmental Glomerulosclerosis: A Systematic Review and Meta-analysis of the Literature. Can J Kidney Health Dis. 2017 Feb 22;4.
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  • Laurin LP, Gasim AM, Derebail VK, McGregor JA, Kidd JM, Hogan SL, Poulton CJ, Detwiler RK, Jennette JC, Falk RJ, Nachman PH. Renal survival in patients with collapsing compared with not otherwise specified FSGS. Clin J Am Soc Nephrol. 2016 Oct 7;11(10):1752-1759.
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  • Laurin LP, Gasim AM, Poulton CJ, Hogan SL, Jennette JC, Falk RJ, Foster BJ, Nachman PH. Treatment with glucocorticoids or calcineurin inhibitors in primary focal segmental glomerulosclerosis. Clin J Am Soc Nephrol. 2016: Mar 7;11(3):386-94.
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  • Laurin LP, Lu M, Mottl AK, Blyth ER, Poulton CJ, Weck KE. Podocyte-associated gene mutation screening in a heterogeneous cohort of patients with sporadic focal segmental glomerulosclerosis. Nephrol Dial Transplant. 2014 Nov;29(11):2062-9.
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  • Laurin LP, Nachman PH, Desai PC, Ataga KI, Derebail VK. Hydroxyurea is associated with lower prevalence of albuminuria in adults with sickle cell disease. Nephrol Dial Transplant. 2014 Jun;29(6):1211-8.
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Education

  • Doctor of Medicine

    Université de Montréal

  • Internal medicine

    Royal College of Physicians and Surgeons of Canada

  • Nephrology

    Royal College of Physicians and Surgeons of Canada

  • Postdoctoral fellowship in glomerular diseases and vasculitis

    University of North Carolina at Chapel Hill

  • MSc in epidemiology

    McGill University

Awards

  • 2017 Junior 1 Clinical Research Scholar  (FRQS – Société québécoise de néphrologie partnership)
  • 2011 Complementary training award  (Faculty of Medicine of Université de Montréal)