Yeast Culture
Coordinator:
Nathalie Tessier
(514) 252-3400 ext. 3334
ntessier.hmr@ssss.gouv.qc.ca
The Yeast Culture Program aims to:
- Conduct studies to reveal new genetic and biochemical factors with regard to cell sensitivity and resistance to different antineoplasic drugs;
- Identify new molecular targets and their particular molecules in basic and medical research projects.
Services
- Yeast haploid mutant tiling intended for studies on antineoplasic drug tolerance such as bleomycin.
- Dissection of yeast tetrads with deletion combinations of genes that are specific to antineoplasic drug resistance.
- Analysis on intracellular distribution of antineoplasic drugs previously marked in tissue biopsies.
- Validation of the different multiple gene expression profiles (about 30) in a single sample.
- Purification of proteins and of selected protein complexes.
Equipment
- Automated pipetting platform
- Yeast micromanipulator
- Zeiss Axio Observer microscope with analysis software
- Multiple gene expression analysis device (GeXP of Beckman-Coulter)
- FPLC chromatography system




