Pascal-André Vendittoli

TITLE

• Research Director, Orthopedics Division, University of Montreal
• Assistant Clinical Professor, University of Montreal

EDUCATION

• M.D.
• M.Sc.
• FRSC

RESEARCH INTERESTS

Our key research objective is to establish the value and benefits of new techniques and technology in joint degeneration treatment. Through our research, we wish to participate in the advancement of scientific knowledge and to improve the quality of care given to orthopedic patients. We take a thorough scientific approach with regard to all of our clinical research hypotheses. The majority of our current research protocols are prospective and randomized. We favour evaluation research projects that aim to provide a response to a clinical problem.

We examine and improve new surgical techniques (mini incisions, different access approaches, etc.) and preoperative pain-reducing analgesics. We also wish to determine whether or not traditional surgery techniques, such as hip resurfacing, unicompartimental knee prosthesis and metal-on-metal bearing surface friction, improve function, reduce convalescence time and extend implant lifecycle. Our unique projects consist of several evaluations: functional evaluation in the Gate Laboratory; measuring cobalt, chromium and titanium ions in  blood and urine; evaluating individual clinical outcomes; measuring periprosthetic bone density, x-ray analyses; etc. Our research team is now regarded as a world leader in this research field.

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RESEARCH TEAM

Research Assistants

• Daniel Lusignan, Nurse
• Serge Marquis, Nurse
• Jannie Barry, .B.Sc.

Full-Time Research Investigator

• Marc Therrien, B.Sc., M.Sc.

Students

• Julie Nantel, Ph.D. Student, University of Montreal, Co-director
• Hassan Nasri, Ph.D. Student ETS, Co-director
• Christiane Caouette, M.Sc. Student ETS, Co-director

DISTINCTIONS AND ACHIEVEMENTS

• Junior Investigator Award 1, FRSQ.
• Alexandra Kirkley Prize (COS): Young Investigator Award for outstanding research by a young investigator, 2003.
• Over the last few years, Dr Vendittoli has given more than 125 presentations on his studies in conferences with peer committees. He has received more than 70 invitations to speak at many international conferences.

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Selected papers

Vendittoli P.-A., Makinen P., Drolet P., Lavigne M., Fallaha M., Guertin M.-C., Varin F. A multimodal analgesia protocol for total knee arthroplasty. A randomized, controlled study. J Bone Joint Surg Am. 2006 Feb;88(2):282-9.

Girard J., Lavigne M., Vendittoli P.-A., Roy A.-G. Biomechanical reconstruction of the hip: A randomized study comparing total hip resurfacing and total hip arthroplasty. J Bone Joint Surg Br. 2006 Jun;88-B(6):721-726.

Vendittoli P.-A., Lavigne M., Roy A.-G., Lusignan D. A Prospective Randomized Clinical Trial Comparing Metal-on-Metal Total Hip Arthroplasty and Metal-on-Metal Total Hip Resurfacing in Patients Less Than 65 Years Old. Hip International 2006; vol. 16 (Suppl 4): pages S73 - S81.

Vendittoli P.-A., Lavigne M., Roy A.-G., Girard J. A randomized study comparing resection of acetabular bone at resurfacing and total hip replacement. J Bone Joint Surg Br. 2006, Aug; 88B.

Vendittoli P.-A., Mottard S., Roy A.-G., Dupont C., Lavigne M. Chromium and cobalt ion release following the Durom high carbon content, forged metal-on-metal surface replacement of the hip. J Bone Joint Surg Br 2007;89-4:441-8.

Vendittoli P.-A., Ganapathi M., Lavoie P., Duval N., Roy A., Lavigne M. Randomised study comparing two methods of acetabular cup positioning in total hip arthroplasty. Hip International, October 2007.

Vendittoli P.-A., Lavigne M., Girard J., Lavoie P., Duval N. Prospective randomized clinical study comparing metal on polyethylene versus ceramic on ceramic bearing in THA. Acta Orthop. Belg., 2007, 73, 468-477.

Vendittoli P.-A., Ganapathi M., Nuno N., Plamondon D., Lavigne M. Factors affecting hip range of motion in surface replacement arthroplasty. Clin Biomech (Bristol, Avon) 2007;22-9:1004-12.

Ganapathi M., Vendittoli P.-A., Roy A.-G., Lavigne M. Heterotopic ossification after THA and SRA hip replacement, a randomized study. J Arthroplasty, 2008.

Lavigne M,. Rama R.-K., Ganapathi M., Nuño N., Winzenrieth R., Vendittoli P.-A. Factors affecting acetabular bone loss during primary hip arthroplasty - A quantitative analysis using computer simulation. Clin Biomech (Bristol, Avon). 2008 Feb 21.

Dr Vendittoli has recently published more than 15 scientific articles on hip and knee arthroplasty in journals with peer committees. He is also an external reviewer for three scientific journals.

Complete list of Dr. Venditoli's publications (PubMed)

ADDITIONAL INFORMATION

Grants and Research Contracts

• Recovery after hip arthroplasty: effects of physical exercise on gait pattern, balance and health.
   F. Prince, M. Lavigne, I. Shrier, PA Vendittoli
  CIHR, Planning and Development Grant, Mobility and Aging
  $95 000 (1 year)
• EPCAT study group
  CIHR, Clinical and Random Trials
  Collaborator
  Principal Investigator: David Anderson
  Amount: $1 018 819  
• Startup Grant, Fonds de Recherche en Santé du Québec (FRSQ)
  2007-2010
  Research grant for establishing young investigator awards
  $10 000/year = $30 000  
• And more than a dozen of research contracts in orthopedics with private enterprises.
  

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