Mark Lesk

TITLE

• Associate Professor

EDUCATION

• M.Sc., Weizmann Institute of Science, Israel (1984).
• M.D., McGill University, Montreal (1989).
• Ophtalmology, University of Montreal (1994).
• Fellowship in glaucoma, Wills Eye Hospital, Philadelphia (1995).

RESEARCH INTERESTS

• Influence of blood flow and ocular biomechanics on the optic nerve in glaucoma;
• Development of a new imaging device to measure the biomechanical properties of the optic nerve (patent application submitted);
• Blood flow deficiency in AMD.

RESEARCH TEAM

• Ahmed Bayoumi, Research Fellowship
• Ali Hafez, Ph.D.
• Micheline Deschenes, Ph.D.
• Olivier Fontaine, Ph.D.
• Kanwarpal Singh Chauhan, Ph.D. (co-direction Tsuneyuki Ozaki)
• Jing Wang, M.Sc.
• Ahmed Amar, M.Sc. (co-direction Denis Claude Roy)
• Renaud Manuguerra-Gagne, M.Sc. (co-direction Denis Claude Roy)

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selected papers

Hafez A, Bizzarro RLG, Rivard M, Lesk MR.  Changes in optic nerve head blood flow after therapeutic intraocular pressure reduction in glaucoma patients and ocular hypertensives.  Ophthalmology, 110(1):201-10, 2003.

Harasymowycz PJ, Kamdeu Fansi A, Papamatheakis DG,  Gresset J,  Lesk MR. Validity of screening for glaucomatous optic nerve damage using confocal scanning laser ophthalmoscopy (HRT II) in high risk populations: A Pilot Study.  Ophthalmology, 112(12) 2164-2171, 2005.

Hafez AS, Bizzarro R, Descovich D, Lesk MR. Correlation between finger blood flow and changes in optic nerve Head Blood Flow following Therapeutic Intraocular Pressure Reduction.  J Glaucoma, 14(6) 448-454, 2005.

Lesk MR, Hafez, AS., Descovich D. Relationship between Central Corneal Thickness and Changes of Optic Nerve Head Topography and Blood Flow After Intraocular Pressure Reduction in Open-angle Glaucoma and Ocular Hypertension. Arch Ophthalmol, 124 (11): 1568-1572, 2006.

Lesk MR, Wajszilber M, Deschênes MC. The Effects of Systemic Medications on Ocular Blood Flow. Can J Ophthalmol, Jun;43(3):351-355, 2008.

B.C. Chauhan , F.S. Mikelberg , A.G. Balaszi , R.P. LeBlanc , M.R. Lesk , G.E. Trope, Canadian Glaucoma Study Group. Canadian Glaucoma Study: 2. risk factors for the progression of open-angle glaucoma. Arch Ophthalmol, Aug;126(8):1138-9,2008.

Djafari, F., Lesk, M., Desjardins, D., Harasymowycz, P., Lachaine, J.  Determinants of adherence to glaucoma medical therapy in a long-term patient population.  in press, J. Glaucoma, 2008.

Hafez, A.S. Lesk, M.R. Ocular Techniques used for Measurement of Ocular Blood Flow. In Glaucoma, M. Sherwood R. Hitchings, J. Crowston, Shaarawy, E.(eds) Chapter 14, Elsevier Press, in press, 2008.

Micheline C. Deschênes, Denise Descovich, Michèle Moreau, Louis Granger, George A. Kuchel, Tomi S. Mikkola, Gordon H. Fick, Elvire Vaucher,  and Mark R. Lesk. Effect of Postmenopausal Hormone Therapy on Ocular Blood Flow and Retinal Nerve Fiber Layer Structure in Women and on Retinal Tissue Perfusion in Rats. Manuscript in preparation.

Patent: Lesk, MR,  Wajszilber, M, et Ozaki, T. Apparatus and Method for Measuring a Biomechanical Property of an in vivo Eye, and Method of Diagnosis. World Wide Patent application, May, 2008.

Complete list of Dr Lesk's publications (PubMed) 

ADDITIONAL INFORMATION

Collaborator

• Elvire Vaucher, EOUM

Grants

• NSERC
• MDEIEQ
• FRSQ Vision Health Network
• Glaucoma Foundation San Francisco

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