Jean-Pilippe Lafrance

Office Phone: 514-252-3400 ext.:7737
Fax: 514-251-7094
jean-philippe.lafrance@umontreal.ca

Research Axis  Nephrology
Research Unit  Pharmacoepidemiology and kidney diseases

TITLE

  • Clinical assistant Professor  

EDUCation

  • MD, Université de Montréal (2001).
  • FRCP(C), Internal medecine (2005).
  • Specialist Certificate - Nephrology (CSPQ et FRCPC)(2006).
  • MSc in epidemiology, McGill University (2008).
  • Postdoctorate in phamacoepidemiology, Boston University (2009) 

DISTINCTIONS AND ACHIEVEMENTS

  •  KRESCENT Post-Doctoral Fellowship award 

recheArCh Interests

  • Side effects such as acute kidney injury associated with widely used prescription drugs like non-steroidal anti-inflammatory drugs (NSAIDs).
  • Utilization and side effects of prescription drugs in patients with chronic kidney disease or end-stage kidney disease.
  • Epidemiology and risk factors of infectious complications in patients with renal replacement therapy.
  • Incidence, risk factors and outcomes related to acute kidney injury in patients with chronic kidney disease. 

Selected papers

Lafrance JP, Miller D. Selective and Non-Selective Non-Steroidal Anti-Inflammatory Drugs and the Risk of Hospitalization with Acute Kidney Injury. Pharmacol Drug Safety. 2009: in press.

Bouchard J, Ouimet D, Vallé M, Lafrance JP, Leblanc M, Senécal L, Bonnardeaux A, Mathieu J, Pichette V. Comparison of the prevalence of calcidiol insufficiency in predialysis and osteoporotic populations. Int Urol Nephrol. 2008 Dec 5 [Epub ahead of print].

Rahme E, Lafrance JP, Nedjar H, Rahme G, Morin S. Impact of Study Population on Estimates of Naproxen-Associated Adverse Events. Open Rheumathology. 2008;3: 1-8.

Lafrance JP, Rahme E, Lelorier J, Iqbal S. Vascular Access-Related Infections: Definitions, Incidence Rates and Risk Factors. Am J Kidney Dis. 2008; 52(5): 982-93.

Michaud J, Nolin T, Naud J, Lafrance JP, Leblond F, Himmelfarb J, Pichette V. Effect of Hemodialysis on Hepatic Cytochrome P450 Functional Expression. J Pharmacol Sci. 2008; 108(2): 157-63.

Lafrance JP, Letourneau I, Ouimet D, Bonnardeaux A, Leblanc M, Mathieu N, Pichette V. Successful treatment of encapsulating peritoneal sclerosis with immunosuppressive therapy. Am J Kidney Dis.Feb 2008;51(2):e7-10.

Leblanc M, Lafrance JP, Renald A. Dialyzer fiber bundle volume during hemodialysis using large-surface dialyzers. ASAIO J. Nov-Dec 2006;52(6):646-651.

Lafrance JP, Madore F, Querin S. Lactococcus cremoris Peritonitis in a CAPD Patient. Perit Dial Int. Nov-Dec 2006;26(6):716-717.

Robitaille R, Lafrance JP, Leblanc M. Altered laboratory findings associated with end-stage renal disease. Semin Dial. 2006; 19(5):373-380.

Lafrance JP, Leblanc M. Intestinal Manifestations With A Surface-Treated AN69 Membrane And ACEI During Hemodialysis. Nephrol Dial Transplant. 2006 ;21(10):2999-3000.

Complete list of Dr Lafrance's publications (Pubmed)

ADDITIONAL INFORMATIONS

Clinical Duty

Nephrologist, Division of Nephrology, Hôpital Maisonneuve-Rosemont

Research Grants

Utilisation du Registre canadien des insuffisances et des transplantations d'organes (RCITO) et des banques de données administratives provinciales pour l’évaluation des complications reliées à la dialyse.
Fonds de la Recherche en Santé du Québec (FRSQ).
Principal Investigator
Total: 196 219$
07/2009 - 06/2012

Interplay of Chronic Illness, Race, Age and Sex in Glycemic Control.
Veterans Health Administration Health Services Research & Development (HSR&D)
Co-investigator (Principal Investigator: Leonard Pogach, MD)
Total 900 000$
10/2009-09/2012

In-hospital use of nephrotoxic medications and risk of acute kidney injury.
Fonds de la Recherche en Santé du Québec (FRSQ).
Co-investigator (Principal Investigator: Elham Rahme, PhD)
Total: 80 000$
09/2008 - 08/2010

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