Édouard Kouassi

TITLE

• Pharmacist
• Assistant Professor

EDUCATION

• B.Sc., Pharmacy, University of Montreal (1979).
• M.Sc., Pharmacology, University of Montreal (1981) under the supervision of Dr. Gilles Caillé.
• Diplôme d'Études Approfondies (DEA), Immunopharmacology and Immunotoxicology, Université Claude-Bernard, Lyon, France (1982) under the supervision of Dr. Louis Léry.
• Ph.D., Pharmacology, University of Montreal (1985) under the supervision of Dr. Gilles Caillé and Dr. Louis Léry.
• Ph.D., Pharmaceutical Sciences, Université Claude-Bernard, Lyon, France (1990) under the supervision of Prof. Jean-Pierre Revillard.
• Postdoctoral Internship in Immunology, INSERM U80, Lyon, France (1985-1990) under the supervision of Prof. Jean-Pierre Revillard.

RESEARCH INTERESTS

Molecular basis for the relationship between the brain and the immune system: implications for treating neuroinflammatory and neuropsychiatric diseases.

RESEARCH TEAM

Post-doctorate:

• Guy-Bernard Bantsiele

Graduate Students:

• Marie-Ève Koué
• Raouf Igué
• Ingrid Agbato
• Nancy Zaour

Undergraduate Interns:

• Jose-Mario Capo-Chichi

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DISTINCTIONS AND ACHIEVEMENTS

Research Career Award in Health Sciences, Medical Research Council of Canada (MRCC) and Pharmaceutical Manufacturing Association of Canada (PMAC), 1992-1997.

selected papers

Potvin S., Stip E, Sepehry A.A., Gendron A., Bah R., Kouassi E. Inflammatory cytokine alterations in schizophrenia: a systematic quantitative review. Biological Psychiatry, 63: 801-808, 2008.

Landau A.M., Luk K.C., Jones M.L., Siegrist-Johnstone R., Young Y.K., Kouassi E., Rymar V.V., Dagher A., Sadikot A.F., and Desbarats J. Defective Fas expression exacerbates neurotoxicity in a model of Parkinson's disease. The Journal of Experimental Medicine 202: 575-581, 2005.

Abdouh M., Albert P.R., Drobetsky E., Filep J.G., and Kouassi E. 5-HT1A-mediated promotion of mitogen-activated T and B cell survival and proliferation is associated with increased translocation of NF-kappaB to nucleus. Brain, Behavior, and Immunity, 18 : 24-34, 2004.

Gendron A., Kouassi E., Nuara S., Cossette C., D'angelo G., Geadah D., du Souich P., and Teitelbaum J. Transient middle cerebral artery occlusion influence on systemic oxygen homeostasis and erythropoiesis in Wistar rats. Stroke 35: 1979-1984, 2004.

Gendron A., Teitelbaum J., Cossette C., Nuara S., Dumont M., du Souich P., Geadah D., and Kouassi E. Temporal effects of left versus right middle cerebral artery occlusion on spleen lymphocyte subsets and mitogenic responses in Wistar rats. Brain Research 955: 85-97, 2002.

Moisan E., Arbour S., Nguyen N., Hébert M.J., Girard D., Bernier J., Fournier M., and Kouassi E. Prolongation of human neutrophil survival by low-level mercury via inhibition of spontaneous apoptosis. Journal of Toxicology and Environmental Health, Part A, 65: 183-203, 2002.

Abdouh M., Storring J.M., Riad M., Paquette Y., Albert P.R., Drobetsky E., and Kouassi E. Transcriptional mechanisms for induction of 5-HT1A receptor mRNA and protein in activated B and T lymphocytes. Journal of Biological Chemistry 276: 4382-4388, 2001.

Goulet A.C., Goldmacher V.S., Lambert J.M., Roy D.C., Baron C., and Kouassi E. Conjugation of blocked ricin to an anti-CD19 monoclonal antibody increases antibody-induced cell calcium mobilization and CD19 internalization. Blood 90: 2364-2375, 1997.

Kouassi E., and Revillard J.P. Contribution of ß-adrenoceptors to the dopamine-induced elevation of cyclic 3'5'-adenosine monophosphate levels in mouse lymphocytes. Eur. J. Pharmacol. 144: 97-100, 1987.

Kouassi E., Caillé G., Léry L., Larivière L., and Vézina M. Novel assay and pharmacokinetics of levamisole and p-hydroxylevamisole in human plasma and urine. Biopharm. Drug Disp. 7: 71-89, 1986.

Complete list of Dr Kouassi's publications (PubMed)

ADDITIONAL INFORMATION

Funding from AstraZeneca, Research Program in Mental Health and Addiction.

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