Ph.D. in Neuronal Death Signaling and Differentiation
Term: full time
Project description:
The Department of Ophthalmology and the Department of Pathology and Cellular Biology of the University of Montreal have a new laboratory that is looking for highly motivated graduate students, who wish to explore new frontiers in the fields of vision sciences and neurosciences. Leonard A. Levin, Associate Professor, is studying the death cell signaling mechanism following axonal damage; a common mechanism in many diseases such as glaucoma, multiple sclerosis and brain tumors that lead to irreversible blindness. He is also studying the differentiation of retinal ganglion cells using stem cells with the objective of restoring vision.
Qualifications:
M.Sc. in Biology Sciences or equivalent.
The student must be highly motivated, and demonstrate the ability to be creative and to work independently.
Grant: the candidate will be paid according to the Centre’s salary range attributed to graduate students.
Publications:
Lieven CJ, Hoegger MJ, Schlieve CR, Levin LA. Retinal ganglion cell axotomy induces an increase in intracellular superoxide anion. Invest Ophthalmol Vis Sci. 2006 Apr;47(4):1477-85.
Frassetto LJ, Schlieve CR, Lieven CJ, Utter AA, Jones MV, Agarwal N, Levin LA. Kinase-dependent differentiation of a retinal ganglion cell precursor. Invest Ophthalmol Vis Sci. 2006 Jan;47(1):427-38.
Levin LA. Neuroprotection and regeneration in glaucoma. Ophthalmol Clin North Am. 2005 Dec;18(4):585-96, vii. Review.
Swanson KI, Schlieve CR, Lieven CJ, Levin LA. Neuroprotective effect of sulfhydryl reduction in a rat optic nerve crush model. Invest Ophthalmol Vis Sci. 2005 Oct;46(10):3737-41.
Conley L, Geurs TL, Levin LA. Transcriptional regulation of ceruloplasmin by an IL-6 response element pathway. Brain Res Mol Brain Res. 2005 Oct 3;139(2):235-41.
Posting date: April 1, 2008
If you are interested, please send your cover letter, resume and university transcript by e-mail to:
Dr Leonard Levin , Research Investigator
Maisonneuve-Rosemont Hospital Research Centre
5415 Assomption Boulevard, Montreal, QC H1T 2M4
E-mail: leonard.levin@umontreal.ca